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Abstract #1590

Assessment of Cervical Cancer using BOLD MR Imaging - R2* Texture analysis

James Brittin1, Elizabeth Sadowski1, Kristin Bradley2, and Jessica Robbins1

1Radiology, University of Wisconsin, Madision, WI, United States, 2Radiation Oncology, University of Wisconsin, Madision, WI, United States

In our study of patients with cervical cancer, after initial treatment, tumors that recurred tended to have a higher heterogeneity on BOLD R2* maps, and tended to have a positive skew in their image histogram. As tumors undergo treatment, the AUC and skewness decreases significantly. Our findings indicate that BOLD MRI texture analysis can be used to assess long-term response to therapy after initial treatment and to follow tumors during treatment. Further studies using BOLD MRI texture analysis in cervical cancer may help elucidate the utility of this technique in the course of treatment of women with cervical cancer.

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