Free Breathing Multi-parametric quantitative Assessment of Mesothelioma with MRI
Ravi Teja Seethamraju1, Noreen Dunham2, Donna Oka2, Aida Faria2, and Ritu Randhawa Gill2
1MR R&D, Siemens Healthcare, Boston, MA, United States, 2Radiology, Brigham and Women's Hospital, Boston, MA, United States
We demonstrate that free breathing multi-parametric quantitative assessment
of mesothelioma with MRI is feasible. DCE imaging of the thorax with 3D Radial
stack of stairs gradient echo (radial VIBE) sequence can be acquired while free breathing and the resulting pharmacokinetic
maps are of higher diagnostic value than current standard of 2D or 3D FLASH
acquisitions without the need for co-registration. Similarly DWI with readout segmented EPI (RESOLVE) provides similar diagnostic value with a free breathing acquisition. These two biomarkers help improve the evaluation of tumor in mesothelioma patients.
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