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Abstract #1605

Free Breathing Multi-parametric quantitative Assessment of Mesothelioma with MRI

Ravi Teja Seethamraju1, Noreen Dunham2, Donna Oka2, Aida Faria2, and Ritu Randhawa Gill2

1MR R&D, Siemens Healthcare, Boston, MA, United States, 2Radiology, Brigham and Women's Hospital, Boston, MA, United States

We demonstrate that free breathing multi-parametric quantitative assessment of mesothelioma with MRI is feasible. DCE imaging of the thorax with 3D Radial stack of stairs gradient echo (radial VIBE) sequence can be acquired while free breathing and the resulting pharmacokinetic maps are of higher diagnostic value than current standard of 2D or 3D FLASH acquisitions without the need for co-registration. Similarly DWI with readout segmented EPI (RESOLVE) provides similar diagnostic value with a free breathing acquisition. These two biomarkers help improve the evaluation of tumor in mesothelioma patients.

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