Abstract #1669

Investigation of functional baseline neuronal specificity and small-scale network in human primary motor cortex at 7T

Chan Hong Moon¹, Jung-Hwan Kim^1,2, and Kyongtae Ty Bae^1,2

¹Radiology, University of Pittsburgh, Pittsburgh, PA, United States, ²Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States

Compound signal, BOLD (e.g., de-oxygenation, CBF and CBV) has different neuronal specificity depending on the major source. At high-field such as 7T, stimulus-evoked BOLD (fMRI) is known to be more localized to cortex region mainly due to suppression of short T2* signals in large draining vessels. It is question whether spontaneous-evoked BOLD during resting status (rsfMRI) can be localized to neural response and the correlation with fMRI activation. In this study, we investigated BOLD source during resting status in primary motor cortex using high-resolution 7T, and additionally the advantage of 7T rsfMRI in small-scale brain connectivity.

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