Abstract #1678

Age related fluctuation energy and variation of dynamic functional connectivity

Yuanyuan Chen¹, Weiwei Wang¹, Xin Zhao¹, Miao Sha¹, Yanan Liu¹, Peng Zhou¹, Hongyan Ni², and Dong Ming¹

¹Tianjin University, Tianjin, China, People's Republic of, ²Tianjin First Central Hospital, Tianjin, China, People's Republic of

To reveal the age related changes of dynamic function connectivity during rest, five networks were extracted from resting stated fMRI data of 36 young people and 32 old people. The sliding window was carefully selected and the FC variation and the fluctuation energy in detailed frequency band were statistically compared. Decreased FCV and slowing fluctuation in inter-networks were mainly found in old group. OCC and CON, OCC and FP were the most consistent inter-networks between this two age related changes. We concluded that FCV and fluctuation energy had provided a new perspective of aging research.

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