Abstract #1738

Concurrent fMRI, [11C]raclopride-PET and deep brain stimulation of the ventral tegmental area

Christin Y. Sander¹, John Arsenault², Bruce R. Rosen¹, Joseph B Mandeville¹, and Wim Vanduffel¹

¹Radiology, Massachusetts General Hospital, Boston, MA, United States, ²Radiology, Massachusetts General Hospital, Charlestown, MA, United States

Deep brain stimulation (DBS) through implantable neurostimulation electrodes that affect dopaminergic control is an important symptomatic therapy in movement disorders, and has been shown to affect reinforcement learning and motivation. In this study, we employ concurrent DBS in the ventral tegemental area during simultaneous PET/fMRI to understand dopaminergic signature of DBS.

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