Abstract #1746

Should volumetric, slice-wise or non-linear registration be used for motion correction of fMRI data?

Malte Hoffmann¹ and Stephen J Sawiak^1,2

¹Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, United Kingdom, ²Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, United Kingdom

Motion corruption leads to major artefacts in fMRI which are damaging in studies. Most processing pipelines employ linear registration of the brain volume at each time point. As slices are acquired individually, however, it is possible for each slice to require a different transformation. Here, we compared the efficacy of linear volume registration, independent slice-based registration and volume non-linear registration for retrospective correction of fMRI acquisitions using data from forty non-cooperative patients with substantial motion.

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