Abstract #1797

Simultaneous Reconstruction of Activity and Attenuation Involving MRI Information as a Prior

Rong Guo¹, Pei Han¹, Yicheng Chen², Jinsong Ouyang³, Georges El Fakhri³, and Kui Ying¹

¹Engineering Physics, Tsinghua University, Beijing, China, People's Republic of, ²UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, United States, ³Center for Advanced Radiological Sciences, Massachusetts General Hospital, Boston, MA, United States

The maximum likelihood activity and attenuation (MLAA) method usually utilizes time-of-flight (TOF) information to solve the problem of attenuation correction. However, the application of TOF brings noise. In this work, we proposed a method, Maximum a Posteriori for simultaneous activity and attenuation reconstruction (MAPAA), which introduces MRI information as prior knowledge into MLAA to reduce noise.

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