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Abstract #1797

Simultaneous Reconstruction of Activity and Attenuation Involving MRI Information as a Prior

Rong Guo1, Pei Han1, Yicheng Chen2, Jinsong Ouyang3, Georges El Fakhri3, and Kui Ying1

1Engineering Physics, Tsinghua University, Beijing, China, People's Republic of, 2UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, Berkeley, Berkeley, CA, United States, 3Center for Advanced Radiological Sciences, Massachusetts General Hospital, Boston, MA, United States

The maximum likelihood activity and attenuation (MLAA) method usually utilizes time-of-flight (TOF) information to solve the problem of attenuation correction. However, the application of TOF brings noise. In this work, we proposed a method, Maximum a Posteriori for simultaneous activity and attenuation reconstruction (MAPAA), which introduces MRI information as prior knowledge into MLAA to reduce noise.

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