Abstract #1810

Three dimensional T1 and T2* mapping of human lung parenchyma using interleaved saturation recovery and dual echo ultrashort echo time imaging

Neville D Gai¹, Ashkan A Malayeri¹, and David A Bluemke¹

¹Radiology & Imaging Sciences, NIH, Bethesda, MD, United States

Lung T1/T2* may be useful in discriminating between normal and pathological tissue particularly in disorders such as fibrosis, edema or emphysema. Quantitative mapping of the lung parenchyma is challenging due to the low proton density, respiratory and cardiac motion and susceptibility effects. Here we describe a technique based on segmented respiratory triggered 3D ultrashort echo time dual-echo radial imaging interleaved with and without a WET saturation pulse to estimate T1 and T2* maps simultaneously in a single scan. The results show that T1/T2* mapping of lung parenchyma can be reliably performed with relatively high resolution in a clinically feasible time.

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