Abstract #1828

Myelin Water Fraction with Bipolar Multiecho sequences using k-space shift correction

Hongpyo Lee¹, Yoonho Nam², Min-Oh Kim¹, Dongyeob Han¹, and Dong-Hyun Kim¹

¹School of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea, Republic of, ²Department of Radiology, Seoul St. Mary Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of

Recently, myelin water fraction was investigated using multi-echo GRE data. Generally, to ensure phase consistency among the echoes, multi-echo acquisitions use unipolar gradients. However, these unipolar gradient multi-echo sequences reduce acquisition efficiency and increase echo spacing. Bipolar gradients would be preferential however, k-space misregistration induced by readout gradient delays and eddy-currents make phase errors, so severe artifacts occur in myelin water imaging. In this abstract, we present a MWI using bipolar gradient multi-echo GRE sequence with k-space shift correction. Compared to unipolar MWF, k-space shift corrected bipolar MWF yields a reduction in ΔTE, which leads to improved SNR and more accurate quantification.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.