Hongpyo Lee1, Yoonho Nam2, Min-Oh Kim1, Dongyeob Han1, and Dong-Hyun Kim1
1School of Electrical and Electronic Engineering, Yonsei University, Seoul, Korea, Republic of, 2Department of Radiology, Seoul St. Mary Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of
Recently, myelin water fraction was investigated
using multi-echo GRE data. Generally, to ensure phase consistency among the
echoes, multi-echo acquisitions use unipolar gradients. However, these unipolar
gradient multi-echo sequences reduce acquisition efficiency and increase echo
spacing. Bipolar gradients would be preferential however, k-space
misregistration induced by readout gradient delays and eddy-currents make phase
errors, so severe artifacts occur in myelin water imaging. In this abstract, we
present a MWI using bipolar gradient multi-echo GRE sequence with k-space shift
correction. Compared
to unipolar MWF, k-space shift corrected bipolar MWF yields a reduction in ΔTE, which leads to
improved SNR and more accurate quantification.
