Abstract #1878

Magnetic Susceptibility Artefact Correction of Spin-Echo and Gradient-Echo EPI Images

Gary George McGinley^1,2, Atle Bjørnerud^3,4, and Øystein Bech Gadmar³

¹Institute for Experimental Medical Research, Oslo University Hospital, Oslo, Norway, ²KG Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway, ³The Intervention Centre, Oslo University Hospital, Oslo, Norway, ⁴Department of Physics, University of Oslo, Oslo, Norway

This study aims to compare the effectiveness of three reverse-gradient method susceptibility artefact correction tools (EPIC, TOPUP, and HySCO) in the correction of spin-echo (SE) and gradient-echo (GE) EPI images of the brain, and to measure the effect of pixel bandwidth, SENSE factor and slice thickness on artefact correction. This was achieved by co-registering the artefacted and corrected images to an anatomical scan and measuring the normalised mutual information (NMI). It was found that EPIC correction resulted in the largest gains in NMI and that more mutual information was recovered at lower pixel bandwidths after EPIC correction.

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