Abstract #1882

B1-Insensitive Simultaneous Multi-Slice DWI at 7T using SEAMS PINS

Rebecca Emily Feldman¹, Hadrien A Dyvorne¹, Rafael O'Halloran¹, and Priti Balchandani¹

¹Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States

The higher signal-to-noise-ratio offered at 7T, has been shown to increase the resolution of diffusion MRI as well as the precision and directional certainty of diffusion-based parameters. Two major drawbacks of 7T dMRI include lengthy acquisitions and signal loss due to B₁-inhomogeneity. SMS methods reduce the duration of the acquisition, the refocusing pulses typically used in dMRI are particularly sensitive to B1 non-uniformities leading to a loss in signal, or even complete signal dropout in parts of the image. We have created a dMRI sequence with SEAMS PINS and an EPI readout that provides improved immunity to B₁-inhomogeneity.

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