1State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan Inst Phys & Math, Chinese Acad Sci, Wuhan, China, People's Republic of, 2School of Physics, Huazhong University of Science and Technology, Wuhan, China, People's Republic of
SNR and resolution are two important parameters
for the quantitative assessment of MR images. In k-space, the central
part contributes SNR, whereas the edges contribute details. The accuracy
of the apparent diffusion coefficient (ADC) calibration was significantly
affected by SNR. For hyperpolarized GRE sequences, the homogeneous
variable flip angle scheme is sub-optimal and leads to low SNR
images. We propose a simple method termed inhomogeneous variable flip
angle (I-VFA) to derive ADC of hyperpolarized gases. Higher SNR images and more
stable results can be achieved by this simple method.
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