Abstract #1964

Application of the inhomogeneous variable flip angle (I-VFA) scheme in hyperpolarized 129Xe DWI

Jianping Zhong^1,2, Weiwei Ruan¹, Xianping Sun¹, Chaohui Ye^1,2, and Xin Zhou¹

¹State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan Inst Phys & Math, Chinese Acad Sci, Wuhan, China, People's Republic of, ²School of Physics, Huazhong University of Science and Technology, Wuhan, China, People's Republic of

SNR and resolution are two important parameters for the quantitative assessment of MR images. In k-space, the central part contributes SNR, whereas the edges contribute details. The accuracy of the apparent diffusion coefficient (ADC) calibration was significantly affected by SNR. For hyperpolarized GRE sequences, the homogeneous variable flip angle scheme is sub-optimal and leads to low SNR images. We propose a simple method termed inhomogeneous variable flip angle (I-VFA) to derive ADC of hyperpolarized gases. Higher SNR images and more stable results can be achieved by this simple method.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.