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Abstract #1976

High Resolution Cervical Spine DTI in Axial View using Non-triggered Multi-shot Acquisition and SYMPHONY Reconstruction

Xiaodong Ma1, Zhe Zhang1, Yuhui Xiong1, Erpeng Dai1, Yishi Wang1, Le He1, Chun Yuan1,2, and Hua Guo1

1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, People's Republic of, 2Vascular Imaging Laboratory, Department of Radiology, University of Washington, Seattle, WA, United States

In this study, 2D-navigated multi-shot EPI is used to achieve high resolution DTI in the cervical spine without cardiac triggering. A k-space reconstruction method, SYnergistic iMage reconstruction with PHase variatiOn and seNsitivitY (SYMPHONY), is used to correct the ghost artifacts caused by phase variations among different shots. The proposed technique is validated using quantitative analysis in healthy volunteers. Because no cardiac triggering is used, the scan time can be reduced. The improved spatial resolution and scan efficiency are beneficial for the quantitative evaluation of cervical spine in both neuroscience research and clinical diagnosis.

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