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Abstract #1978

Effects of variations in gestational age and birth anthropometric indicators on diffusion metrics of term neonatal white matter: a cohort study

Chao Jin1, Yanyan Li1, Xianjun Li1,2, Miaomiao Wang1, Jie Gao1, Qinli Sun1, and Jian Yang1

1Department of Radiology, the First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China, People's Republic of, 2Department of Biomedical Engineering, School of Life Science and Technology, University of Xi'an Jiaotong, Xi'an, China, People's Republic of

During the life span, brain development would be affected by numerous intra- and inter- factors in a short- or/and long-term period. To reveal typical birth indicators’ short-term effects, the effects of gestational age (GA), birth weight, crown-heel length and head circumference on term neonatal white matter were investigated by DTI. Results indicate that term neonates born with higher GA, birth weight and crown-heel length may hint better maturation of brain microstructure; among four birth indicators, GA was the main factor that influenced DTI-metrics. Particularly, longer crown-heel length with leftward superiority in corona radiata may presumably support early motor function.

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