Abstract #2058

Anisotropic fractional-motion-based diffusion MRI in the human brain

Yun Liu¹, Yang Fan^1,2, and Jia-Hong Gao¹

¹Peking University, Beijing, China, People's Republic of, ²MR Research China, GE Healthcare, Beijing, China, People's Republic of

Several anomalous diffusion models, both empirical and theoretical, were proposed to explain the departure from purely mono-exponential decay of DWI signal in biological tissues. Recently, a fractional motion (FM) based diffusion MRI theory was proposed, which was claimed to be a proper model in the description of diffusion processes in biological systems. However, the tensorial properties of FM related parameters is still unknown. In this work, diffusion magnetic field gradients were applied in several non-linear directions to acquire DWI images. Then, the FM-based parameters were obtained in each diffusion direction and found direction dependent.

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