Abstract #2112

Investigation of temperature dependent changes in signal intensity, T1 and T2* in cortical bone

Henrik Odéen¹, Bradley Bolster², Eun Kee Jeong¹, and Dennis L Parker¹

¹Utah Center for Advanced Imaging Research, Department of Radiology, University of Utah, Salt Lake City, UT, United States, ²Siemens Healthcare, Salt Lake City, UT, United States

Measurements of changes in signal intensity and T1 relaxation time with temperature has been suggested for temperature monitoring in cortical bone during MR guided focused ultrasound treatments. In this study we compare changes in signal intensity, T1, and T2* with temperature using a 3D ultrashort echo time pulse sequence and a 2D gradient recalled echo pulse sequence with short TE. The effects of T1 and T2* change with temperature counteract each other making the change in signal intensity small, and therefore T1 and T2* appears to have the greatest sensitivity to changes in temperature.

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