Abstract #2114

MRI-guided robotic arm (MgRA) to target deep brain nuclei in vitro

Yi Chen^1,2, Filip Sobczak¹, and Xin Yu^1,2

¹Research Group of Translational Neuroimaging and Neural Control, High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, ²Graduate School of Neural Information Processing, University of Tuebingen, Tuebingen, Germany

A key challenge of the fiber optic-mediated multi-model fMRI methodologies is locating the fiber tip accurately and precisely to target deep brain nuclei. The requirement of precision is only several hundreds of microns in the animal brains. In this work, a multi degree of freedom robotic arm was developed with the use of step motors. The setup is in compatible with 14.1T MRI scanner. This MRI-guided robotic arm provides visually monitored fiber insertion to reduce the position error significantly in the perfused rat brain.

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