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Abstract #2188

Extension of the MR field-of-view with HUGE for MR-based attenuation correction in integrated PET/MR

Maike E. Lindemann1, Jan Ole Blumhagen2, and Harald H. Quick1,3

1High Field and Hybrid MR Imaging, University Hospital Essen, Essen, Germany, 2Siemens Healthcare GmbH, Erlangen, Germany, 3Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany

In quantitative PET-imaging, it is essential to correct the attenuation of photons in tissue. In combined PET/MR-imaging the attenuation correction (AC) is based on MR-data and subsequent tissue class segmentation. The MR-FOV is limited due to B0-inhomogeneities and gradient nonlinearities. Therefore, the AC-map is truncated and reconstructed PET-data are biased. HUGE (B0-Homogenization using gradient enhancement), which determines an optimal readout gradient to compensate gradient nonlinearities, is evaluated in phantom experiments and applied to MR-imaging of volunteers. The extension of the MR-FOV for MR-based AC showed an improvement of PET-quantification in integrated PET/MR-imaging by reducing the truncated areas of the AC-map.

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