Abstract #2188

Extension of the MR field-of-view with HUGE for MR-based attenuation correction in integrated PET/MR

Maike E. Lindemann¹, Jan Ole Blumhagen², and Harald H. Quick^1,3

¹High Field and Hybrid MR Imaging, University Hospital Essen, Essen, Germany, ²Siemens Healthcare GmbH, Erlangen, Germany, ³Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany

In quantitative PET-imaging, it is essential to correct the attenuation of photons in tissue. In combined PET/MR-imaging the attenuation correction (AC) is based on MR-data and subsequent tissue class segmentation. The MR-FOV is limited due to B0-inhomogeneities and gradient nonlinearities. Therefore, the AC-map is truncated and reconstructed PET-data are biased. HUGE (B0-Homogenization using gradient enhancement), which determines an optimal readout gradient to compensate gradient nonlinearities, is evaluated in phantom experiments and applied to MR-imaging of volunteers. The extension of the MR-FOV for MR-based AC showed an improvement of PET-quantification in integrated PET/MR-imaging by reducing the truncated areas of the AC-map.

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