Abstract #2244

In vivo 1H MRS using 3 Tesla to investigate the metabolic profiles of joint fluids in different types of knee diseases

Geon-Ho Jahng¹, Wook Jin¹, Dong-Cheol Woo², Chanhee Lee¹, Chang-Woo Ryu¹, and Dal-Mo Yang¹

¹Department of Radiology, Kyung Hee University Hospital at Gangdong, Kyung Hee University, Seoul, Korea, Republic of, ²Biomedical Research Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Korea, Republic of

To assess the ability of proton MR spectroscopy to identify the apparent heterogeneous characteristics of metabolic spectra in effusion regions in human knees using a high-field MRI system, 84 patients with effusion lesions underwent proton MRS with PRESS single-voxel MRS using a clinical 3.0 Tesla MRI system. Nonparametric statistical comparisons were performed to investigate any differences in metabolites among the degenerative osteoarthritis, traumatic diseases, infectious and an inflammatory disease groups. There were no significant differences among the three groups for the CH3 (p=0.9019), CH2 (p=0.6406), and CH=CH lipids (p=0.5467) and water (p=0.2853).

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