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Abstract #2272

A new method for accurate detection of cartilage lesions in femoroacetabular impingement using quantitative T2 mapping: preliminary validation against arthroscopic findings at 3 T

Noam Ben-Eliezer1,2, Akio Ernesto Yoshimoto2, KAI Tobias Block1,2, Roy Davidovitch3, Thomas Youm3, Robert Meislin3, Michael Recht1,2, Daniel K Sodickson1,2, and Riccardo Lattanzi1,2

1Center for Advanced Imaging Innovation and Research (CAI2R), New York University School of Medicine, New York, NY, United States, 2Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 3Department of Orthopedic Surgery, New York University Hospital for Joint Diseases, New York, NY, United States

Early diagnosis of cartilage defects is critical for the success of corrective surgical procedures in patients with femoroacetabular impingement (FAI). T2 is a biomarker for early biochemical degeneration of cartilage, but in vivo T2 mapping is challenging while commonly used techniques based on exponential fit of multi spin-echo protocols are inaccurate. We used a Bloch simulation based T2 mapping technique – the EMC algorithm – to retrospectively quantify reliable T2 values in the hip cartilage of FAI patients. We then defined a normalized T2-index using an internal reference and showed that it allows detection of surgically confirmed cartilage lesions with 95% accuracy.

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