Meeting Banner
Abstract #2328

Development of Calibrationless Parallel Imaging Methods for Clinical Hyperpolarized Carbon-13 MRI Studies

Yesu Feng1, Jeremy Gordon1, Peter Shin1, Cornelius von Morze1, Michael Lustig2, Peder E.Z. Larson1, Michael A. Ohliger1, Lucas Carvajal1, James Tropp3, John M Pauly4, and Daniel B. Vigneron1

1Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States, 2EECS, UC Berkeley, Berkeley, CA, United States, 3GE Healthcare, Fremont, CA, United States, 4Electrical Engineering, Stanford, Stanford, CA, United States

Hyperpolarized (HP) 13C imaging requires fast data acquisition due to the fast T1 relaxation. Parallel imaging methods are well suited for acceleration of data acquisition, yet conventional parallel imaging schemes require explicit calibration of coil sensitivity which presents significant challenge to HP 13C imaging. In this study, a calibrationless parallel imaging method was tested and applied to HP 13C MRI. A 2-fold acceleration was achieved when this technique was applied together with a 2D EPI readout. This strategy is being extended for 3D HP 13C EPI for improved volumetric coverage and better temporal resolution for future clinical studies.

This abstract and the presentation materials are available to members only; a login is required.

Join Here