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Abstract #2401

2D Relaxometry and Diffusivity of Human Knee Synovial Fluid after ACL-injuries Studied Using HR-MAS NMR

Kaipin Xu1, Subramaniam Sukumar1, John Kurhanewicz1, and Xiaojuan Li1

1Radiology, University of California, San Francisco, San Francisco, CA, United States

To better understand the pathological progression of osteoarthritis (OA), techniques based on high resolution magic angle spinning (HR-MAS) NMR spectroscopy are developed for the study of relaxation times (T1, T2, and T1ρ) and diffusion coefficient (D) of human knee synovial fluids (SF) harvested from 1 OA and 8 anterior cruciate ligament (ACL) injured patients.

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