Abstract #2401

2D Relaxometry and Diffusivity of Human Knee Synovial Fluid after ACL-injuries Studied Using HR-MAS NMR

Kaipin Xu¹, Subramaniam Sukumar¹, John Kurhanewicz¹, and Xiaojuan Li¹

¹Radiology, University of California, San Francisco, San Francisco, CA, United States

To better understand the pathological progression of osteoarthritis (OA), techniques based on high resolution magic angle spinning (HR-MAS) NMR spectroscopy are developed for the study of relaxation times (T1, T2, and T1ρ) and diffusion coefficient (D) of human knee synovial fluids (SF) harvested from 1 OA and 8 anterior cruciate ligament (ACL) injured patients.

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