Abstract #2421

7T MRS AND 18F AV45 PET NEURONAL MARKERS IN ELDERLY HIV+ SUBJECTS: EFFECTS OF SEROSTATUS AND COGNITIVE IMPAIRMENT

Mona A Mohamed¹, Peter B Barker¹, Richard L Skolasky², Heidi Vornbrock Roosa³, Yun Zhou¹, Weiguo Ye¹, Noble George¹, James Brasic¹, Dean F Wong¹, and Ned Sacktor³

¹Radiology, Johns Hopkins Medical Institutions, Baltimore, MD, United States, ²Orthopedics, Johns Hopkins Medical Institutions, Baltimore, MD, United States, ³Neurology, Johns Hopkins Medical Institutions, Baltimore, MD, United States

In this study, 7T MRS and 18F AV45 PET were used to measure brain metabolites and amyloid burden in Elderly HIV subjects. These reliable biomarkers can be used in assessing the relation between normal aging, HIV and the degree of HIV Associated Neurocognitive Disorders (HAND).

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