Abstract #2478

A compact and easy to handle set-up for high quality MR Elastography of the breast.

Jurgen H Runge¹, Jules L Nelissen^2,3, Larry de Graaf², Barbara Molenkamp⁴, Suzan van der Meij⁴, Klaas Nicolay², Gustav J Strijkers³, Jaap Stoker¹, Anneloes E Bohte¹, Aart J Nederveen¹, Ondrej Holub⁵, and Ralph Sinkus⁵

¹Radiology, Academic Medical Center, Amsterdam, Netherlands, ²Biomedical NMR, Eindhoven University of Technology, Eindhoven, Netherlands, ³Preclinical and Translational MRI, Academic Medical Center, Amsterdam, Netherlands, ⁴Surgery, Academic Medical Center, Amsterdam, Netherlands, ⁵Biomedical Engineering, King's College London, London, United Kingdom

Distinction between benign and malignant breast lesions remains difficult with conventional (dynamic) contrast-enhanced MRI. MR Elastography (MRE) can distinguish benign and malignant tissues based on their viscoelastic properties but breast MRE has not found widespread use in daily clinical practice, because of the complex equipment required and cumbersome data acquisition. Here we present a compact, easy to handle breast MRE set-up that allows the acquisition of high quality, artefact-free MRE data. This set-up was designed, built and tested at two different institutions in volunteers and a patient.

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