Abstract #2487

MR measurements of luminal water in prostate gland

Shirin Sabouri¹, Ladan Fazli^2,3, Silvia Chang^4,5, Richard Savdie³, Edward Jones⁶, Larry Goldenberg^2,3, and Piotr Kozlowski^2,3,4,7

¹Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, ²Vancouver Prostate Centre, Vancouver, BC, Canada, ³Urologic Sciences, University of British Columbia, Vancouver, BC, Canada, ⁴Radiology, University of British Columbia, Vancouver, BC, Canada, ⁵Vancouver General Hospital, Vancouver, BC, Canada, ⁶Pathology, Vancouver General Hospital, Vancouver, BC, Canada, ⁷UBC MRI Research Center, Vancouver, BC, Canada

Measurement of relative amount of lumen in prostatic tissue can provide useful information for diagnosing of many prostatic diseases. Using multi-exponential T₂ mapping, the fractional volume of the luminal space, or so called luminal water fraction (LWF), in the prostatic tissue can be determined. In order to use the LWF as a proportional representative of the true percentage of lumen, it is important to investigate the correlation between the two parameters. We have acquired and analyzed MR images of 10 subjects, and found a significant correlation between the LWF and the percentages of lumen in tissue.

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