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Abstract #2487

MR measurements of luminal water in prostate gland

Shirin Sabouri1, Ladan Fazli2,3, Silvia Chang4,5, Richard Savdie3, Edward Jones6, Larry Goldenberg2,3, and Piotr Kozlowski2,3,4,7

1Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, 2Vancouver Prostate Centre, Vancouver, BC, Canada, 3Urologic Sciences, University of British Columbia, Vancouver, BC, Canada, 4Radiology, University of British Columbia, Vancouver, BC, Canada, 5Vancouver General Hospital, Vancouver, BC, Canada, 6Pathology, Vancouver General Hospital, Vancouver, BC, Canada, 7UBC MRI Research Center, Vancouver, BC, Canada

Measurement of relative amount of lumen in prostatic tissue can provide useful information for diagnosing of many prostatic diseases. Using multi-exponential T2 mapping, the fractional volume of the luminal space, or so called luminal water fraction (LWF), in the prostatic tissue can be determined. In order to use the LWF as a proportional representative of the true percentage of lumen, it is important to investigate the correlation between the two parameters. We have acquired and analyzed MR images of 10 subjects, and found a significant correlation between the LWF and the percentages of lumen in tissue.

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