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Abstract #2547

Measurement of Plaque Burden using 3D SNAP vessel wall MRI

Niranjan Balu1, Jie Sun1, Daniel S Hippe1, Huijun Chen2, and Chun Yuan1

1Radiology, University of Washington, Seattle, WA, United States, 2Tsinghua University, Beijing, China, People's Republic of

We have developed a single sequence (SNAP) for identification of high-risk features such as stenosis, intraplaque hemorrhage and juxtaluminal calcification. However measurement of plaque burden, an early marker for disease, required a separate black-blood scan. In this work, we demonstrate that plaque burden can be measured using an alternate reconstruction (SNAP2). In patients with atherosclerosis, we compare vessel wall area measurements on SNAP2 to established black-blood MRI measurements and show that our method provides results comparable to established plaque MRI methods.

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