Abstract #2580

Towards Plaque and Thrombus Imaging with Hybrid of Opposite-Contrast (HOP) MR Angiography at 7T

Sören Johst¹, Karsten H Wrede^1,2, Harald H Quick^1,3, and Mark E Ladd^1,4

¹Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany, ²Department of Neurosurgery, University Hospital Essen, Essen, Germany, ³High Field and Hybrid MR Imaging, University Hospital Essen, Essen, Germany, ⁴Medical Physics in Radiology, German Cancer Research Center (dkfz), Heidelberg, Germany

Imaging of intracranial plaques and thrombi is important, as they play a role e.g. in rupture risk of cerebral aneurysms. 7T provides the potential to increase spatial resolution due to increased SNR. A time-of-flight MR angiography (TOF MRA) sequence was extended to a hybrid of opposite-contrast MRA sequence providing two contrasts, bright and black blood. Inverting and subtracting both contrasts makes thrombi/plaques visible. Sufficient flow dephasing moments for black-blood contrast were determined for three resolutions, image post-processing was implemented, and contrast evaluated. This approach potentially enables patient studies with higher resolution than previously achievable while maintaining reasonable acquisition times.

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