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Abstract #2580

Towards Plaque and Thrombus Imaging with Hybrid of Opposite-Contrast (HOP) MR Angiography at 7T

Sören Johst1, Karsten H Wrede1,2, Harald H Quick1,3, and Mark E Ladd1,4

1Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, Germany, 2Department of Neurosurgery, University Hospital Essen, Essen, Germany, 3High Field and Hybrid MR Imaging, University Hospital Essen, Essen, Germany, 4Medical Physics in Radiology, German Cancer Research Center (dkfz), Heidelberg, Germany

Imaging of intracranial plaques and thrombi is important, as they play a role e.g. in rupture risk of cerebral aneurysms. 7T provides the potential to increase spatial resolution due to increased SNR. A time-of-flight MR angiography (TOF MRA) sequence was extended to a hybrid of opposite-contrast MRA sequence providing two contrasts, bright and black blood. Inverting and subtracting both contrasts makes thrombi/plaques visible. Sufficient flow dephasing moments for black-blood contrast were determined for three resolutions, image post-processing was implemented, and contrast evaluated. This approach potentially enables patient studies with higher resolution than previously achievable while maintaining reasonable acquisition times.

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