Abstract #2586

Characterization of Pulsatile Cerebrospinal Fluid Motion Among Young, Elderly and Idiopathic Normal Pressure Hydrocephalus By Correlation Mapping Technique

Satoshi Yatsushiro¹, Saeko Sunohara², Naokazu Hayashi³, Akihiro Hirayama³, Mitsunori Matsumae³, Afnizanfaizal Bin Abdullah⁴, and Kagayaki Kuroda²

¹Course of Science and Technology, School of Science and Technology, Tokai University, Hiratsuka, Kanagawa, Japan, ²Course of Electrical and Electronic Engineering, Graduate School of Engineering, Tokai University, Hiratsuka, Kanagawa, Japan, ³Department of Neurosurgery, Tokai University School of Medicine, Isehara, Kanagawa, Japan, ⁴Department of Software Engineering, Faculty of Computing, Universiti Teknologi Malaysia, Johor Bahru, Malaysia

Correlation mapping technique composed of delay time and correlation coefficient mapping to characterize propagation properties of cerebrospinal fluid (CSF) motion was applied to young, elderly healthy and idiopathic normal pressure hydrocephalus (iNPH) patient groups for classification. Brightness of the color of maximum correlation map was adjusted according to the amplitude of the CSF velocity waveform for assisting clinicians to understand the propagation properties intuitively. The groups were classified by quantifying the standard deviation of the correlation distributing in the intracranial CSF space. The technique was expected to classify diseases related to CSF dynamics such as iNPH.

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