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Abstract #2591

Kinetic Energy Distributions in Fontan Circulation - Evaluation of Respiration Effects

Alejandro Roldán-Alzate1,2, Eric Schrauben3,4, Oliver Wieben2,3, and Christopher J Francois2

1Mechanical Engineering, University of Wisconsin - Madison, Madison, WI, United States, 2Radiology, University of Wisconsin - Madison, Madison, WI, United States, 3Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, 4Centre for Advanced MRI, Auckland, New Zealand

The purpose of this study was to evaluate changes in blood flow and kinetic energy distribution between inspiration and expiration in TCPC patients for assessing efficiency of the system using 4D flow MRI. Six TCPC patients were imaged using a PC-VIPR scheme that allows for double gating to the ECG and respiratory cycles providing flow data for separate respiratory phases. Results exhibit greater respiratory-induced flow changes within a single subject than previous work has shown in the same analysis performed on healthy controls, suggesting that respiration plays a larger role in regulating flow in these patients.

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