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Abstract #2598

Perioperative assessment of aortic tissue at risk for dysfunction in patients undergoing valve and/or aortic replacement using 4D flow MRI

Emilie Bollache1, Paul W.M. Fedak2,3, Pim van Ooij1, David Guzzardi2, S. Chris Malaisrie3, Alex Hong1, Patrick M. McCarthy3, James Carr1, Jeremy Collins1, Michael Markl1,4, and Alex J. Barker1

1Department of Radiology, Northwestern University, Chicago, IL, United States, 2Department of Cardiac Sciences, University of Calgary, Calgary, AB, Canada, 3Division of Surgery-Cardiac Surgery, Northwestern University, Chicago, IL, United States, 4Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States

The effect of the type of aortic surgery in patients with aortopathy is not well known. We studied 23 patients who underwent 4D flow MRI both before and after aortic valve (AVR) and/or ascending aortic (AAR) replacement, from which we estimated the pre- and post-surgical area of aortic ‘at-risk’ tissue, with an elevated wall shear stress. After surgery, in most AVR patients, at-risk tissue area was decreased while in most AAR patients, it was increased. This pilot study suggests the usefulness of 4D flow MRI to provide longitudinal aortic hemodynamic follow-up after surgery, which should be confirmed in larger populations.

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