Abstract #2598

Perioperative assessment of aortic tissue at risk for dysfunction in patients undergoing valve and/or aortic replacement using 4D flow MRI

Emilie Bollache¹, Paul W.M. Fedak^2,3, Pim van Ooij¹, David Guzzardi², S. Chris Malaisrie³, Alex Hong¹, Patrick M. McCarthy³, James Carr¹, Jeremy Collins¹, Michael Markl^1,4, and Alex J. Barker¹

¹Department of Radiology, Northwestern University, Chicago, IL, United States, ²Department of Cardiac Sciences, University of Calgary, Calgary, AB, Canada, ³Division of Surgery-Cardiac Surgery, Northwestern University, Chicago, IL, United States, ⁴Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States

The effect of the type of aortic surgery in patients with aortopathy is not well known. We studied 23 patients who underwent 4D flow MRI both before and after aortic valve (AVR) and/or ascending aortic (AAR) replacement, from which we estimated the pre- and post-surgical area of aortic ‘at-risk’ tissue, with an elevated wall shear stress. After surgery, in most AVR patients, at-risk tissue area was decreased while in most AAR patients, it was increased. This pilot study suggests the usefulness of 4D flow MRI to provide longitudinal aortic hemodynamic follow-up after surgery, which should be confirmed in larger populations.

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