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Abstract #2600

Turbulent wall shear stress assessment using 4D flow MRI

Magnus Ziegler1,2, Jonas Lantz1,2, Tino Ebbers1,2, and Petter Dyverfeldt1,2

1Division of Cardiovascular Medicine, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden, 2Centre for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden

Chaotic velocity fluctuations caused by turbulent blood flow create fluctuations in the shear stress acting on the vascular wall. This turbulent wall shear stress can cause vascular remodeling and increased endothelial cell turnover. This work explores the use of MR-estimated turbulent kinetic energy (TKE) for mapping the turbulent wall shear stress. Time-resolved velocity data for non-pulsatile flow was obtained using computational fluid dynamics in two patient-derived geometries and used to simulate PC-MRI measurements. Near-wall TKE was estimated using a novel sampling method and was found to correlate strongly to turbulent wall shear stress, opening new avenues for analysis.

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