Abstract #2649

Integrating dynamic contrast-enhanced magnetic resonance imaging and diffusion kurtosis imaging for neoadjuvant chemotherapy assessment in nasopharyngeal carcinoma

Dechun Zheng¹, Yunbin Chen¹, Meng Liu¹, Qiuyuan Yue¹, Xiaoxiao Zhang¹, Hao Lin¹, Xiangyi Liu¹, Wang Ren¹, Weibo Chen², and Queenie Chan³

¹Radiology, Fujian Provincial Cancer Hospital, Fuzhou, China, People's Republic of, ²Philips Healthcare, Shanghai, China, People's Republic of, ³Philips Healthcare, Hong Kong, Hong Kong

DKI is an emerging technique and shows advantage than traditional DWI. Prior DCE-MRI studies suggested it had utility in early monitoring radiotherapy and chemotherapy sensitivity in anti-tumor treatment. However, there are a few studies investigated whether a combination of multi-modalities functional MRI techniques could improve diagnostic efficacy for prediction of anti-tumor outcome. This study enrolled 53 patients who received both DCE-MRI and DKI exams during NAC courses and suggested there were collaboration between DCE-MRI and DKI to early monitor NAC treatments in NPC. In addition, two NAC cycles is a better time point to non-invasive assess NAC response using fMRI.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.