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Abstract #2702

A Validation Study of Real-time Phase Contrast MRI with Low-Rank Modeling

Aiqi Sun1, Bo Zhao2, Yunduo Li1, Qiong He1, Zechen Zhou1, Shuo Chen1, Rui Li1, and Chun Yuan1,3

1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua Universiy, Beijing, China, People's Republic of, 2Martinos Center for Biomedical Imaging, Harvard Medical School, Chalestown, MA, United States, 3Department of Radiology, University of Washington, Seattle, WA, United States

Conventional phase-contrast (PC) MRI method relies on ECG-synchronized cine acquisition to acquire data over multiple cardiac cycles. The underlying spatiotemporal averaging limits this method to studying pathological irregularities. Real-time PC-MRI is a promising approach to overcome these limitations. Although several techniques have been developed to real-time PC-MRI, few have been fully validated due to the difficulty of acquiring a reference data set as gold standard. This study aims at validating the accuracy of a novel real-time PC-MRI technique through both flow phantom experiments and in vivo experiments.

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