Abstract #2710

Using MRI to Observe Increased Venous Flow Collateralization in Subjects with Anomalous Jugular Veins

SEAN KUMAR SETHI¹, Giacomo Gadda², Ana M. Daugherty³, David T. Utriainen¹, Jing Jiang¹, Naftali Raz³, and Ewart Mark Haacke⁴

¹The MRI Institute of Biomedical Research, Detroit, MI, United States, ²Physics, University of Ferrara, Ferrara, Italy, ³Department of Gerontology, Wayne State University, Detroit, MI, United States, ⁴Biomedical Engineering, Wayne State University, Detroit, MI, United States

We have established in previous works that a subset of multiple sclerosis (MS) patients show abnormal structure and flow in the internal jugular veins (IJV) when measured with MRI. In this retrospective analysis, we classified and compared extracranial venous collateral flow in MS and normal control samples using MR venography and Phase-contrast flow quantification with a large, standardized dataset. Over 50% of the MS cohort shows a jugular anomaly. The stenotic-MS group shows reduced Type I venous flow compared to healthy controls and non-stenotic MS, while having elevated Type II and Type III flows.

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