Abstract #2712

Contrast-Enhanced 4D Flow Imaging with Reduced Fat Signal

Joseph Y. Cheng¹, Tao Zhang¹, Adam B. Kerr², Michael Lustig³, John M. Pauly², and Shreyas S. Vasanawala¹

¹Radiology, Stanford University, Stanford, CA, United States, ²Electrical Engineering, Stanford University, Stanford, CA, United States, ³Electrical Engineering & Computer Sciences, University of California, Berkeley, CA, United States

Volumetric time-resolved velocity imaging (4D flow) can be used as a single comprehensive sequence to quantify blood flow, evaluate cardiac function, and assess anatomy. However, fat signal can reduce tissue contrast, introduce high-signal-intensity artifacts from motion, and cause errors in velocity quantification. Two approaches are presented for reducing fat signal in contrast-enhanced 4D flow imaging with minimal time penalty. The first approach is a short spectral-spatial RF pulse that reduces fat signal below the level of contrast-enhanced blood pool. The second approach is the introduction of one additional echo with a different TE to separate fat/water for all flow encoding echoes. The performance of these approaches are evaluated in a static phantom study and in patient volunteer studies.

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