3D Printed Patient-Specific Model for In Vitro Hemodynamic Studies and Comparison with In Vivo Findings Using 4D Flow MRI
Rouzbeh R Ahmadian1, Austin P Boyd2, Jeremy D Collins1, James C Carr1, Alex J Barker1, and Michael Markl3
1Radiology, Northwestern University, Chicago, IL, United States, 2Northwestern University, Chicago, IL, United States, 3Radiology & Biomedical Engineering, Northwestern University, Chicago, IL, United States
The advent of 3D printing has opened exciting possibilities for biomedical applications. One of the most intriguing of these possibilities is the ability to use images obtained from radiology scanners (CT or MR) to create 3D models of patient anatomy followed by 3D printing. These models will have all the same geometries of patient anatomy to very high detail. In order to have practical applications, however, these 3D models need to behave similarly to human tissue under standard conditions. Our research utilizes patient-specific 3D printed models in an in vitro fluid dynamic circuit to compare 4D Flow MRI data to that of the patient (in vivo). This direct comparison will allow for validation of the 3D printed model for further biomedical application.
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