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Abstract #2749

Time-Efficient Reduced-Distortion Prostate Diffusion MRI Using Reduced Field-of-View Readout-Segmented EPI

Novena Rangwala1, Kyunghyun Sung1, and Holden Wu1

1Department of Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States

The purpose of this study was to minimize echo planar imaging (EPI)-related distortion artifacts while maintaining the time-efficiency for prostate diffusion-weighted MRI (DWI) using a reduced field of view (rFOV) readout-segmented EPI (RESOLVE) technique. Image distortions in clinical standard DW single-shot (ss) EPI (5:52min) were compared with a matched RESOLVE protocol (seven segments, 7:03min) and rFOV RESOLVE (five segments, 4:59min) using the Dice similarity coefficient (DSC) on forward and reverse phase-encoded images. DSC was significantly higher (0.91±0.05) in rFOV RESOLVE compared with the other protocols, indicating that rFOV RESOLVE can improve DWI quality and visualization in the prostate compared with ss-EPI, with higher time efficiency than regular RESOLVE.

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