Abstract #2857

Investigation of intrascanner reproducibility of quantitative susceptibility mapping (QSM) and R2* at 3T

Xiang Feng¹, Andreas Deistung¹, Marianne Cleve¹, Ferdinand Schweser^2,3, and Juergen Reichenbach¹

¹Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany, ²Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, United States, ³MRI Molecular and Translational Research Center, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, United States

In the present work, we quatitatively assessed the reproducibility of Quantitative susceptibility mapping (QSM) and effective transverse relaxation rate (R2*) in healthy volunteers at 3T scanner during multiple scanning sessions. We also investigated the QSM normalization based on 2 reference structures, Cerebrospinal fluid (CSF) and frontal White Matter (fWM).Our results indicated that QSM using CSF as reference region reveals increased scan-rescan reliability than referencing with fWM.

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