Abstract #2875

The potential of arterial spin labeling with full labeling duty cycle (FDC-ASL) to measure blood flow and transit delay simultaneously with substantially improved sensitivity and efficiency

Jia Guo¹, Richard B. Buxton¹, and Eric C. Wong^1,2

¹Radiology, UC San Diego, La Jolla, CA, United States, ²Psychiatry, UC San Diego, La Jolla, CA, United States

Pulsed arterial spin labeling (PASL) has the potential to achieve full labeling duty cycle with almost instant labeling. We explore here a new PASL-based fast labeling and imaging method for measuring blood flow (BF) and transit delay (TD) simultaneously, through a series of simulations. The results show that the BF and the TD can be accurately estimated. This new approach shows promise for substantially improved sensitivity and efficiency compared with conventional methods using PASL or pseudo-continuous ASL.

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