Abstract #2884

Pharmacokinetic modeling driven Rapid Adaptive Spatio-Temporal Resolution for Accelerated (RASTRA) DCE-MRI

Rashmi Reddy¹, Imam Shaik¹, Nithin N Vajuvalli¹, Dharmendra Kumar K C¹, and Sairam Geethanath¹

¹Dayananda Sagar Institutions, Bangalore, India

The proposed method combines Compressed Sensing (CS) framework with view sharing to accelerate Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCEMRI). A novel method to combine k-spaces of different regions (Temporal Region (TR) and Spatial Region (SR)) is carried out in this work. View sharing is adapted to combine the kspace, by mapping samples from SR region frames onto corresponding frames in TR region to improve the edge information, achieving better reconstruction with higher acceleration. It is shown that the proposed method provides better Pharmacokinetic(PK) maps at higher acceleration rates than existing methods with minimum error, as qualified by NRMSE values.

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