Abstract #2946

MRI-based Estimation of Liver Function by Intravoxel Incoherent Motion Diffusion-weighted Imaging

Jing Zhang¹, Yikai Xu¹, Yihao Guo², Yanqiu Feng², Queenie Chen³, Yingjie Mei^2,4, Xiangliang Tan¹, Jiajun Zhang¹, Xixi Zhao¹, Zeyu Zheng¹, and Chunhong Wang¹

¹Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, People's Republic of, ²School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China, People's Republic of, ³Philips Healthcare, Hong Kong, China, People's Republic of, ⁴Philips Healthcare, Guangzhou, China, People's Republic of

The quantitative evaluation of hepatic function is important for monitoring patients and preoperative assessment of the hepatic reserve. This work aims to assess the sensitivity of IVIM in evaluating liver function in patients with chronic liver disease. The results demonstrate that perfusion-related parameters (D* and f) are useful for indicating the severity of liver disease, and may have the potential to become a promising non-invasive tool for monitoring liver function.

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