Abstract #2953

Liver MR imaging using 3D phase-sensitive inversion recovery (PSIR) sequence

Yasuhiro Fujiwara¹, Hirotoshi Maruyama², Nobuyuki Kosaka³, Yoshiyuki Ishimori⁴, and Noriyuki Furukawa²

¹Department of Medical Imaging, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan, ²Radiological Center, National Hospital Organization Kumamoto Medical Center, Kumamoto, Japan, ³Department of Radiology, University of Fukui, Fukui, Japan, ⁴Department of Radiological Sciences, Ibaraki Prefectural University of Health Sciences, Ibaraki, Japan

We applied 3D phase-sensitive inversion recovery (PSIR) sequence to liver MR imaging. Experiments with phantom and healthy subjects revealed that this sequence improved contrast enhancements of Gd-based agents and liver-to-spleen or muscle contrasts while simultaneously providing an accurate T1 map of the liver. Better Gd contrast enhancements and liver contrasts may improve tumor-to-liver contrasts in the hepato-biliary phase with Gd-based hepatocyte-specific contrast agents, and the accurate T1 map may be useful for liver-function assessments. Although a clinical study is required to evaluate its utility, this sequence may have potential to improve liver MR imaging.

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