Abstract #2957

Use of Intravoxel Incoherent Motion (IVIM) in Evaluation of Histological Differentiation of Hepatocellular Carcinoma (HCC) in Patients with Hepatitis B Virus Infection

Qungang Shan¹, Tianhui Zhang¹, Yong Zhang², Yunhong Shu³, Zhuang Kang¹, Bingjun He¹, Jingbiao Chen¹, Zhenyu Zhou², and Jin Wang¹

¹Department of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China, People's Republic of, ²GE Healthcare China, Beijing, China, People's Republic of, ³Mayo Clinic, Rochester, MN, United States

Among the various causes of hepatocellular carcinoma (HCC), hepatitis B virus (HBV) infection is the most common one in Asian countries including China. We assessed the correlation of ADC and IVIM parameters with the histological differentiation of HBV-related HCCs. Our results showed that ADC, D and f coefficients are significantly correlated with histological differentiation of HBV-related HCC. According to ROC analysis, ADC, D and f were useful parameters for the evaluation of histological differentiation of HCCs. ADC showed better diagnostic performance compared with D and f IVIM is a promising tool for predicting histological differentiation of HBV-related HCC.

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