Abstract #2971

Correlation between intravoxel incoherent motion (IVIM) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters in rectal cancer

Yanyan Xu¹, Hongliang Sun¹, Kaining Shi², and Wu Wang¹

¹Radiology, China-Japan Friendship hospital, Beijing, China, People's Republic of, ²Philips Healthcare China, Beijing, China, People's Republic of

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has been applied in rectal cancer for the purpose of characterizing tumor perfusion[1]. However, DCE-MRI should use intravenous contrast media based gadolinium, which will increase the risk of kidney systemic fibrosis[2]. The bi-exponential analysis in intravoxel incoherent motion (IVIM) model can separate microscopic circulation perfusion with pure water diffusion[3-4]. Correlation has been derived between the IVIM perfusion parameters f and D* and the classical perfusion parameters[5-6]. However, its relationship with DCE-MRI parameters in rectal cancer has not been clarified.

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