Abstract #2979

Correcting for the Effect of Motion using Simultaneous Image Registration and Model Estimation (SIR-ME) in Abdominal DW-MRI

Sila Kurugol¹, Moti Freiman¹, Onur Afacan¹, Liran Domachevski², Jeanette M. Perez-Rossello¹, Michael J. Callahan¹, and Simon K. Warfield¹

¹Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, United States, ²Nuclear Medicine, Rabin Medical Center, Petah-Tikva, Israel

Quantitative diffusion-weighted MRI (DW-MRI) has been increasingly used for the detection and characterization of abdominal abnormalities. However, respiratory, cardiac and peristalsis motion deteriorates robustness and reproducibility of parameter estimation in DW-MRI. Current solutions do not entirely correct for motion and have disadvantages such as increased scan time. In this work, we introduce a simultaneous image registration and model estimation (SIR-ME) framework for motion-compensated parameter estimation. The proposed method improved the goodness-of-fit by more than 50% and estimated model parameters more precisely, resulting in better discrimination between normal and diseased bowel loops, which will potentially impact clinical utilization.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.