Meeting Banner
Abstract #3057

Evaluation of tractography using Fiberfox for whole brain connectome analysis

Hu Cheng1, Ahmad Abdulrahman M Alhulail2, and Sharlene Newman1

1Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, United States, 2Department of Physics, Indiana University, Bloomington, IN, United States

Due to the complexity of brain microstructure and organization, the validation of tractography results remains a challenging problem. In this work, effect of SNR and b value of diffusion imaging on the variability and errors of tractography was evaluated through a software phantom developed by Tractometer. Three fiber tracking algorithms based on DTI, CSD, and Q-sampling were tested. Large false positive and false negative rate was seen for all methods, regardless of SNR or b value. A moderate thresholding can reduce false positive rate and total error rate.

This abstract and the presentation materials are available to members only; a login is required.

Join Here