Abstract #3063

Construction of a diffusion MRI brain template using Human Connectome Project database

Yung-Chin Hsu¹ and Wen-Yih Isaac Tseng¹

¹Institute of Medical Device and Imaging, National Taiwan University College of Medicine, Taipei, Taiwan

The present study uses the diffusion data of the human connectome project (HCP) as well as a state-of-the-art registration strategy to develop a diffusion template in the ICBM-152 space. A total of 489 diffusion datasets were included in the template construction. The HCP diffusion template matches to the ICBM-152 space well, in both the deep and superficial white matter regions. In addition, this template is capable of revealing detailed diffusion-dependent structures, such as the cortical-depth dependence of general fractional anisotropy (GFA). The HCP diffusion template is potentially useful in segmenting fine fiber tracts and parceling thalamic nuclei or hippocampal subfields.

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