Abstract #3066

A comparison of multiple acquisition strategies to overcome B1 inhomogeneities in diffusion imaging of post-mortem human brain at 7T

Sean Foxley¹, Saad Jbabdi¹, Moises Hernandez Fernandez¹, Connor Scott², Olaf Ansorge², and Karla Miller¹

¹FMRIB Centre, University of Oxford, Oxford, United Kingdom, ²Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom

In this work we compare a single flip angle and dual flip angle approach to overcome B1 inhomogeneities in DW-SSFP data of post mortem human brain at 7T. Both approaches were designed and optimized to achieve optimal CNR with whole brain coverage. The single flip angle approach displayed slight improvements in orientation estimates; however, the dual flip angle approach is being further investigated as a potential source of microstructural estimates with little to no cost in orientation.

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