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Abstract #3108

Assessment of longitudinal reproducibility of mice LV functional parameters @11.7T derived from self-gated CINE MRI

Zhi Zuo1,2,3, Anne Subgang2,3, Alireza Abaei3, Gen-shan Ma1, and Volker Rasche2,3

1Department of Cardiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, China, People's Republic of, 2Department of Internal Medicine II, University Hospital Ulm, Ulm, Germany, 3Core Facility Small Animal MRI, Medical Faculty, Ulm University, Ulm, Germany

Cardiovascular magnetic resonance (CMR) has emerged as the most accurate imaging modality for noninvasive assessments of left ventricular (LV) structure and function in mice. However, data on the longitudinal variability of LV systolic function assessment in mice is still limited. In this contribution, a one year follow-up of the longitudinal reproducibility of the LV function and mass has been performed at 11.7T with self-gated CINE MRI. The investigated protocol was proven reliable for the evaluation of EF, EDV, ESV, SV and LVM data.

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