Abstract #3130

Quantitative, Time-efficient, Heart-Rate Independent Myocardial BOLD MRI with Whole-heart Coverage at 3T in a Canine Model of Coronary Stenosis with Simultaneous 13N-Ammonia PET Validation

Hsin-Jung Yang¹, Damini Dey¹, Jane Sykes², John Butler², Xiaoming Bi³, Behzad Sharif¹, Sotirios Tsaftaris⁴, Debiao Li¹, Piotr Slomka¹, Frank Prato², and Rohan Dharmakumar¹

¹Cedars Sinai Medical Center, Los Angeles, CA, United States, ²Lawson Health Research Institute, london, ON, Canada, ³Siemens Healthcare, Los Angeles, CA, United States, ⁴IMT Institute for Advanced Studies Lucca, Lucca, Italy

Current myocardial BOLD MR methods are limited by: (a) poor spatial coverage and imaging speed; (b) imaging confounders; and (c) imaging artifacts, particularly at 3T. To address these limitations, we developed a heart-rate independent, free-breathing 3D T2 mapping technique at 3T that utilizes near 100% imaging efficiency, which can be completed in 3 minutes with full LV coverage. We tested our method in a canine model of coronary stenosis and validated our findings with simultaneously acquired13N-ammonia PET perfusion data in a whole-body PET/MR system.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.