Hsin-Jung Yang1, Damini Dey1, Jane Sykes2, John Butler2, Xiaoming Bi3, Behzad Sharif1, Sotirios Tsaftaris4, Debiao Li1, Piotr Slomka1, Frank Prato2, and Rohan Dharmakumar1
1Cedars Sinai Medical Center, Los Angeles, CA, United States, 2Lawson Health Research Institute, london, ON, Canada, 3Siemens Healthcare, Los Angeles, CA, United States, 4IMT Institute for Advanced Studies Lucca, Lucca, Italy
Current myocardial BOLD MR methods are limited by: (a)
poor spatial coverage and imaging speed; (b) imaging confounders; and (c)
imaging artifacts, particularly at 3T. To address these limitations, we
developed a heart-rate independent, free-breathing 3D T2 mapping
technique at 3T that utilizes near 100% imaging efficiency, which can be
completed in 3 minutes with full LV coverage. We tested our method in a canine
model of coronary stenosis and validated our findings
with simultaneously acquired13N-ammonia PET
perfusion data in a whole-body PET/MR system.
